PURPOSE To examine the overlap of homologous recombination deficiency (HRD) and microsatellite instability high (MSI-H) status, and to dissect driver versus bystander status of BRCA1/2 mutations (BRCAm) in this context. METHODS A pan-cancer comprehensive genomic profiling cohort (n = 213,199) was examined for overlap between BRCAm and MSI-H status. BRCA1/2 variant zygosity was examined and…
A Study of Adjuvant V940 and Pembrolizumab in Renal Cell Carcinoma (V940-004) – Full Text View.
Breast Cancer: New Horizons, Current Controversies is a comprehensive educational curriculum that encompasses the full range of breast cancer care. Topics include mechanisms of disease,…
Breast Cancer: New Horizons, Current Controversies is a comprehensive educational curriculum that encompasses the full range of breast cancer care. Topics include mechanisms of disease,…
A Study of Adjuvant V940 and Pembrolizumab in Renal Cell Carcinoma (V940-004) – Full Text View.
A Study of Adjuvant V940 and Pembrolizumab in Renal Cell Carcinoma (V940-004) – Full Text View.
Surgery with curative intent constitutes the standard of care for patients with advanced renal-cell carcinoma, yet more than 50% of patients with high-risk features will…
Patients with renal-cell carcinoma who undergo nephrectomy have no options for adjuvant therapy to reduce the risk of recurrence that have high levels of supporting…
With ge nomic and protein biomarker analysis now a cornerstone of personalized cancer care, translational advancements and novel methodologies play a powerful role in improving…
With ge nomic and protein biomarker analysis now a cornerstone of personalized cancer care, translational advancements and novel methodologies play a powerful role in improving…
I’m excited to join this incredible initiative! This organization’s mission is very important to me and I’m proud to help them make a difference. Please…
