An international team of researchers led by scientists at Johns Hopkins University, School of Medicine, have screened a large library of drugs to find farnesol that inhibits PARIS, a protein that increases in patients with Parkinson’s disease. The authors showed farnesylation of PARIS prevented the build up of damaging reactive oxygen species and prevented the loss of dopamine-releasing neurons…
Research shows two class II HDACs regulate cells that produce an important inflammatory cytokine associated with IBD and other disorders.
Speakers at the recent CAR-TCR Summit Europe in London agreed that despite their efficacy, CAR/TCR-T cell therapy faces challenges that can result in high costs,…
A new study shows that increased levels of a protein named TP53INP2 in muscle correlate with greater muscular strength and healthier aging in humans.
Findings suggest regular aspirin use may have an active role in enhancing Immunosurveillance against colorectal cancer.
Used in combination with immune checkpoint therapy, cytokine molecules “step on the gas” to jump-start the immune system’s anticancer response.
Boehringer Ingelheim will apply Ochre Bio’s discovery platform to develop treatments for late-stage metabolic dysfunction-associated steatohepatitis (MASH) cirrhosis and other chronic liver diseases (CLDs), through…
Scientists maintain that findings from using DELiVR have revealed potential therapeutic targets within brain regions.
A new study shows that increased levels of a protein named TP53INP2 in muscle correlate with greater muscular strength and healthier aging in humans.
The interest in the use of organoids to model human development in health and disease is at an all-time high. Recently, a team from the…
Boehringer Ingelheim will apply Ochre Bio’s discovery platform to develop treatments for late-stage metabolic dysfunction-associated steatohepatitis (MASH) cirrhosis and other chronic liver diseases (CLDs), through…
