No, it’s not “statistically implausible” when results differ between studies, or between different groups within a study. | Statistical Modeling, Causal Inference, and Social Science
This letter by Thorland et al. published in the New England Journal of Medicine is rather amusing. It’s unclear to me what their point is, other than the fact that they find the published results for the new COVID drug molnupiravir “statistically implausible.” Background: The pharma company Merck got very promising results for molnupiravir at their interim analysis (~50% reduction in hospitalisation/death) but less promising results at their final analysis (30% reduction). Thorlund et al. were surprised
