NICE issued a final guidance recommending reimbursement of avapritinib monotherapy in adult patients with ASM, SM-AHN, or mast cell leukemia.
Background IFNs could reprogram immunosuppressive myelopoiesis, induce accumulation of APCs with capacity to prime anti-tumor immunity. IFN-α favors a Th1 shift in immunity and concurrent…
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William Gradishar, MD, discusses advances in endocrine therapeutic options for patients with estrogen receptor–positive, HER2-negative breast cancer, in follow-up to his presentation at the Lynn…
Background Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TIL) represents a promising strategy for the treatment of patients with advanced melanoma (MEL). In this study…
Results from the phase 2 SWOG S1011 study demonstrated that extended lymphadenectomy failed to improve survival compared to standard lymphadenectomy among patients with localized muscle-invasive…
Christina S. Baik, MD, MS, discusses the types of HER2 testing that should be performed in NSCLC and the design of the phase 3 Beamion…
‘EL LOTO AZUL’ · ED. FACSIMIL EN B/N COLOREADA · EN FRANCÉS
Background Tumor-infiltrating lymphocyte (TIL) expansion ex vivo is currently performed from surgically excised tumors in culture media containing Interleukin-2 (IL-2). Targeting antigen-presenting cells through CD40…
Joshua K. Sabari, MD, discusses whether individual B7-H3 analysis is available at his institution, noting that, if it is, he obtains IHC for both PD-L1…
The National Cancer Institute approved the following clinical research studies last month. To access this subscriber-only content please log in or subscribe.If your institution…
