Mitochondrial fatty acid oxidation drives senescence
Nuclear DNA damage activates fatty acid–fueled mitochondrial energy metabolism to induce cellular senescence, a hallmark of aging.
Nuclear DNA damage activates fatty acid–fueled mitochondrial energy metabolism to induce cellular senescence, a hallmark of aging.
Rationale A ‘patient-oriented’ research paradigm, also known as patient and public engagement, has infiltrated the field of health sciences and continues to spread. At first…
In this episode of Lung Cancer Considered, host Dr. Stephen Liu and guests preview the publication of the IASLC Ninth Edition of Tumor, Node, and…
During 2000–20, NHS coverage of new drugs displaced more population health than it generated. Our results highlight the inherent trade-offs between individuals who directly benefit…
A Ken Liu, two Adrian Tchaikovsky novels, Succession-style drama (with added telepathy) and a Polish epic. Emily H. Wilson surveys 2025’s sci-fi
The OncoAlert Newsletter is now out for June 23-29, 2023
Dr. Vivek Murthy’s report cites studies linking alcoholic beverages to at least seven malignancies, including breast cancer. But to add warning labels, Congress would have…
Nature Medicine – Machine-learning-based and population-level electronic health record data–based emulation of landmark phase 3 randomized controlled trials (RCTs) in oncology across a range…
Gao et al. show that the plasma cells (PCs) can be recruited to glioblastoma stem cell (GSC) niches via the CCL2-CCR2 chemokine program and promote glioblastoma…
Primary immune thrombocytopenia is an autoimmune disease in which autoreactive B cells play a crucial role in pathogenesis by producing autoantibodies primarily directed against platelet…
“The true measure of healthcare innovation isn’t how many tools we can invent, but how many lives we can improve.” Sven Jungmann There are often…