MAGIC-G1 Study Provides Updated Findings With MTX110 in Recurrent Glioblastoma
An update on PFS and OS data from the phase 1 MAGIC-G1 study of MTX110 in recurrent glioblastoma has been released.
An update on PFS and OS data from the phase 1 MAGIC-G1 study of MTX110 in recurrent glioblastoma has been released.
Isa-RVd given as induction treatment without consolidation led to a 30% reduction in the risk of disease progression or death vs RVd in multiple myeloma.
PURPOSESelpercatinib, a highly selective RET kinase inhibitor with CNS activity, is approved in multiple countries for patients with RET fusion–positive non–small cell lung cancer (NSCLC).METHODSPatients…
This cohort study examines whether osimertinib is associated with a higher incidence of cardiac toxic effects compared with earlier-generation epidermal growth factor receptor tyrosine kinase…
Irene Ghobrial, MD, Dana-Farber Cancer Institute, Boston, MA, discusses the new PANGEA 2.0 model, which aims to improve risk stratification of smoldering multiple myeloma (SMM)…
Treatment with navtemadlin lowered the levels of biomarkers of disease burden in patients with relapsed/refractory myelofibrosis.
Acalabrutinib plus venetoclax, with or without obinutuzumab, improved PFS over SOC chemoimmunotherapy in patients with treatment-naive CLL.
PURPOSETrimodal therapy (TMT) is the standard treatment for patients with nonmetastatic inflammatory breast cancer (IBC). TMT consists of neoadjuvant systemic therapy, modified radical mastectomy (MRM),…
Patients with treatment naive DLBCL experienced high response rates when treated with zilovertamab vedotin plus R-CHP and a RP2D dose of the agent was selected.
Tafasitamab plus lenalidomide and rituximab improved median PFS vs lenalidomide and rituximab in patients with relapsed/refractory follicular lymphoma.
Real-world data presented at the 2024 ASH Annual Meeting evaluated the efficacy of the most common treatment sequences in CLL/SLL.