Long-Term Exposure to Ambient Benzene and Mortality
Benzene has been classified as a human carcinogen on the basis of evidence linking it to increased risks of acute myeloid leukemia in adults, as well as positive associations with several other cancer sites (1). Exposure to benzene is ubiquitous; and common sources of exposure include traffic emissions, wood burning, and cigarette smoke; and benzene ranks within the top 20 chemicals in terms of production volume in the United States (2). Although there is a relatively large literature on the health