Leveraging a comprehensive genomic data library for detecting clonal hematopoiesis in liquid biopsy – Tempus
Background: Clonal Hematopoiesis (CH) is a well established confounder in next-generation sequencing (NGS)-based liquid biopsy cancer diagnostics. Misclassification of CH variants as tumor variants can lead to false positive actionable variant detection, potentially resulting in incorrect interpretation of results and therapy selection. Moreover, CH variants may also interfere with quantitative variant monitoring leading to inaccurate … Continued
