Inconsistent Outcome Reporting in Heart Failure Randomized Controlled Trials

Randomized controlled trials (RCTs) are considered the gold standard for assessing the safety and efficacy of medical interventions. Inconsistencies between the prespecified protocol and trial publication can reduce the internal validity of trials. In this study, we sought to assess the prevalence and characteristics of heart failure RCTs that report outcomes different from those prespecified. Of…

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