Rationale: Low arousal threshold and poor muscle responsiveness are common determinants of obstructive sleep apnea (OSA). Hypnotics were hypothesized as an alternative OSA treatment via raising the…
As the largest pan-European meeting of its kind, the Sleep and Breathing Conference is a not-to-be-missed event for respiratory professionals specialising in sleep respiratory medicine…
Vanzacaftor–tezacaftor–deutivacaftor was safe and well tolerated and maintained FEV1 % predicted from elexacaftor–tezacaftor–ivacaftor baseline with further improved CFTR function. Improvements in CFTR function compared with…
“.” American Journal of Respiratory Cell and Molecular Biology, 72(1), pp. 112–115 Supported by Fritz-Thyssen Foundation Postdoc-Stipend 40.22.0.028MN (O.A.) and the Massachusetts General Hospital Department…
Mismatch repair–deficient (dMMR) tumors can be found in 10 to 15% of patients with nonmetastatic colon cancer. In these patients, the efficacy of chemotherapy is…
For children with complex and chronic conditions who are well known to their local medical teams, success sometimes simply looks like becoming well known to…
The incidence of non-malignant pleural effusions far outweighs that of malignant pleural effusions and is estimated to be at least 3-fold higher. These so-called benign…
Patients who receive pulmonary artery catheters (PACs) after cardiac surgery have significantly reduced risk for 1-year mortality.
The author describes the science behind a study of ponsegromab to treat cancer cachexia. Ponsegromab suppresses a pathway in neurons located in specific regions of…
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Background Pulmonary rehabilitation (PR) is an essential element of chronic obstructive pulmonary disease (COPD) management. However, access to conventional face-to-face PR programmes is limited. Methods…
