Health inequalities in 2040
This report explores how patterns of diagnosed ill health vary by socioeconomic deprivation in England and projects these patterns to 2040.
This report explores how patterns of diagnosed ill health vary by socioeconomic deprivation in England and projects these patterns to 2040.
This Medical News article discusses a KFF poll about the public’s exposure to and beliefs about inaccurate health information, as well as media use and…
We are in the midst of a radical and uncomfortable departure from the status quo in obesity. Both progress and problems result.
Identifying metabolic abnormalities that occur before pancreatic ductal adenocarcinoma (PDAC) diagnosis could increase chances for early detection. We collected data on changes in metabolic parameters…
What’s a typical vacation activity for doctors? Work. A new study finds that most physicians do work on a typical day off. In this essay,…
Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor condition that precedes multiple myeloma and related disorders but has also been associated with other…
Systemically administered mRNA aggregates (RNA-LPA) transfect lymphoreticular organs, inducing a massive cytokine/chemokine response that rapidly reprograms the tumor microenvironment while mobilizing dendritic cells/lymphocytes to elicit…
Decision-makers considering using cost-effectiveness analysis (CEA) to inform health-technology assessment (HTA) must contend with documented and controversial shortfalls of CEA, including its assumption of disease…
Cells carrying a monoallelic germline BRCA2 mutation can bypass Knudson’s “two-hit” requirement to initiate tumorigenesis when the glycolytic metabolite methylglyoxal transiently disables BRCA2 function. Metabolic…
DDX41 germline mutations define the most common genetic syndrome predisposing to myeloid neoplasms (MN). Two papers highlight the genetic landscape and pro
INTRODUCTION AND OBJECTIVE:A randomized trial in the transrectal prostate biopsy setting demonstrated no difference in detection of clinically significant prostate cancer (csPC) whether targeted biopsy…