Fourney SINS JCO 2011.full.pdf

Page 2 of 6An evidence-based process using the best available literature and expert-opinion consensus was used to develop the Spine Instability Neoplastic Score (SINS; Table 1).12-14 In this classification system, tumor-related instability is assessed by adding together six individual component scores: spine location, pain, lesion bone quality, radio- graphic alignment, vertebral body collapse,…

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