Criticisms of the US Food and Drug Administration’s accelerated approval process have resurfaced after the recent approval of aducanumab (Aduhelm) for dementia. Elisabeth Mahase finds that the process is plagued by missing efficacy data and questionable evidence Since the US Food and Drug Administration established its accelerated approval pathway for drugs in 1992, nearly half (112) of the 253…
Objectives To answer a national research priority by comparing the risk-benefit and costs associated with reverse total shoulder replacement (RTSR) and anatomical total shoulder replacement…
Guidance on drug safety from regulatory agencies must be sensibly communicated and based on strong, clear evidence Doctors learn early in their careers about the…
We need to define the concept of early diagnosis The importance of early diagnosis, particularly in cancer, has been covered widely in the media. Improving…
Guidelines should be reviewed to identify inappropriate use of race and ethnicity Health systems continue to grapple with the deeply rooted consequences of systemic racism…
Paediatricians and child health professionals are urging the UK government to stop selling arms to Israel and to impose sanctions on produce from illegal Israeli…
It’s a valid question, but their efficacy isn’t the focus here. A major pharmacy chain in Sweden has introduced age restrictions for the purchase of…
Continuity of care—seeing the same GP over time—reduces the need for emergency care and increases longevity in patients.1 It leads to better patient satisfaction and…
Equitable access to fertility care must be recognised as a human right so that it can be better balanced with other societal needs, say Silke…
Plans by the prime minister, Rishi Sunak, to overhaul the sick note system in the UK have left me with mixed emotions. A more independent…
Continuity of care—seeing the same GP over time—reduces the need for emergency care and increases longevity in patients.1 It leads to better patient satisfaction and…
