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The U.S. Preventive Services Task Force’s new recommendation statement on the use of statin therapy for primary prevention in adults aged 40 to 75 years with no history of CVD is similar to its 2016 recommendations.The USPSTF continues to recommend statins for the primary prevention of CVD in patients aged 40 to 75 years with at least one CVD risk factor and 10% or greater 10-year risk for