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Oral and Poster Abstracts 626. Aggressive Lymphomas: Prospective Therapeutic Trials: Poster III Adults, Antibody Therapy, Biological, Clinical Trials, Non-Biological, Lymphomas, Chemotherapy, Clinical Research, Clinically Relevant, Diseases, Immunotherapy, Therapies, Aggressive Lymphoma, Lymphoid Malignancies, Study Population Jason R. Westin, MD1,...

  • 123456 Profile photo of Madelyn

    I want to highlight an exciting prospective trial for frontline treatment of DLBCL which will look at a potential “chemo free” approach. The SmartStop trial will look at the combination of Lenalidomide, Tafasitamab, Rituximab, and Acalabrutinib either alone or in combination with CHOP. There will be a cohort of patients that if they achieve a CR after 4 cycles of the chemo free regimen will go on to an additional 6 cycles of chemo free treatment. Presented here is just the trial design.