Outcomes after first-line immunochemotherapy for primary mediastinal B-cell lymphoma: a LYSA study | Blood Advances | American Society of Hematology

In a retrospective analysis of 313 PMBL treated in France and Belgium R-CHOP14 and R-ACVBP had excellent 3 yr OS. Although limited by retrospective nature and likely patent selection these regimens performed better than R-CHOP21. R-ACVBP was more toxic than RCHOP. Patients with high pretreatment TMTV had worse outcomes.

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