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PubMed

CCM is safe, improves exercise tolerance and quality of life in the specified group of HF patients, and leads to fewer HF hospitalizations. (Evaluate Safety and Efficacy of the OPTIMIZER System in Subjects With Moderate-to-Severe Heart Failure; NCT01381172).

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    A Randomized Controlled Trial to Evaluate the Safety and Efficacy of Cardiac Contractility Modulation