DZD1516 Plus Trastuzumab Deruxtecan Shows Preclinical Synergy in HER2+ Breast Cancer with Brain Metastases

Nicholas P. McAndrew, MD, MSCE, discusses the need for HER2-targeted TKIs specifically designed to penetrate the blood-brain barrier, updated clinical data on the safety and tolerability of DZD1516 monotherapy, and the implications of nonclinical data on DZD1516 for treating CNS metastases in HER2-positive breast cancer.

Read the full article here

Related Articles