Data: Optimal initiation of Paxlovid in hospitalized COVID patients is 3 to 5 days
University of Minnesota http://twin-cities.umn.edu/ 612-625-5000 Taking the SARS-CoV-2 antiviral drug nirmatrelvir-ritonavir (Paxlovid) 3 to 5 days after COVID-19 symptom onset—not earlier or later—may result in the greatest reduction in viral loads, viral transmission, and viral rebound in hospitalized patients, a University of Hong Kong–led study finds. For the study, published by eLife, which publishes peer-reviewed preprints, the investigators fitted a mathematical model of in vivo Omicron variant