Corvia’s RESPONDER-HF Confirmatory Trial Supported by RELIEVE-HF Data
April 22, 2024 — Corvia Medical, Inc, a company dedicated to transforming the treatment of heart failure, welcomes the recent release of V-Wave’s RELIEVE-HF trial data supporting the evidence base around atrial shunt therapy, which is currently under study in the global RESPONDER-HF trial of the Corvia Atrial Shunt. RELIEVE-HF failed to meet its primary efficacy endpoint and did not reduce heart failure events or improve quality of life in heart failure patients with a preserved ejection fraction (HFpEF). However, the results confirmed the importance of selecting patients with characteristics likely to benefit from atrial shunting versus those who will not. “Patient selection is critical, especially in HFpEF,” said Sanjiv Shah, MD, Director of the HFpEF Program at Northwestern University School of Medicine, and co-Principal Investigator of RESPONDER-HF. “We found in our last trial, REDUCE LAP-HF II, that HFpEF patients with pacemakers or pulmonary vascular disease didn’t benefit from a