Cancer Cell | Cell Press
Chronic stress is associated with increased risk of metastasis and poor survival in cancer patients, yet the reasons are unclear. In this paper, Dr. Mikala Egeblad of Johns Hopkins Medicine and colleagues examine how chronic stress increases metastasis in mice, its role in establishing a pro-metastatic lung microenvironment, and how deleting the neutrophil-glucocorticoid receptor abolishes stress-induced metastasis. In summary Chronic stress increases lung metastasis from disseminated cancer cells 2- to