After Cancer Cases, Bluebird Bio Suspends Two Sickle Cell Trials
Bluebird Bio saw its share price plunge by more than one-third after temporarily and voluntarily suspending two clinical trials assessing its LentiGlobin gene therapy for sickle cell disease (SCD; bb1111), following reports that two participants in the earlier-phase study developed blood cancers—one of acute myeloid leukemia (AML), the other of myelodysplastic syndrome (MDS).