Clinical Responses in KRAS-Mutant Solid Cancers

An investigational KRAS inhibitor induced clinical responses in patients with non-small cell lung cancer (NSCLC) and colorectal cancer harboring KRAS mutations, according to the results of a new study. Data demonstrating the efficacy of KRAS inhibitor MRTX849 in preclinical studies and in two patients with solid tumors were published simultaneously in Cancer Discovery (2019; doi:…

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