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Small molecule targeting NaV1.7 via inhibition of… : PAIN
by inhibition of the voltage-gated sodium channel NaV1.7. We previously identified compound 194 as an indirect inhibitor of NaV1.7 by preventing SUMOylation of the NaV1.7-trafficking…
Effectiveness of Ketamine As a Rescue Drug for Patients… : Critical Care Explorations
t. This report details the multiyear experience of paramedics managing midazolam-resistant SE following the introduction of a ketamine-rescue protocol. DESIGN: A 7-year, population-based, observational study…
Blood Transfusion in the Age of Tranexamic Acid: Who Needs a Type and Screen Before Total Hip Arthroplasty?
Modern surgical protocols, particularly the use of tranexamic acid (TXA), have reduced, but not eliminated, blood transfusions surrounding total hip arthroplasty (THA). Identifying patients at…
Borderline Personality Disorder and Loneliness: Broadening… : Harvard Review of Psychiatry
mes. Psychodynamic theories of BPD emphasize fundamental impairment in attachment and interpersonal functioning. Empirical research demonstrates an association between BPD diagnosis and increased loneliness. Individuals…
Transcranial direct current stimulation alleviates the pain … : PAIN Reports
and meta-analysis to comprehensively and quantitatively characterize the effects of tDCS on KOA-related pain. A search strategy based on the Population, Intervention, Comparison, Outcome, and…
January 2025 – Volume 166 – Issue 1 : PAIN
PAIN publishes research on the nature, mechanisms and treatment of pain. The journal provides a forum for the dissemination of research in the basic and…
Incarceration is associated with higher mortality after… : Journal of Trauma and Acute Care Surgery
analysis of incarcerated trauma patients to date and investigates whether incarceration status is an independent risk factor for poor outcomes after trauma for US adults.…
Physical, Cognitive, Emotional, and Social Health Outcomes… : Pediatric Critical Care Medicine
om January 2021 to June 2022. PATIENTS: One hundred thirty-five children (1 mo to 18 yr), admitted for greater than or equal to 48 hours…
BOA response to Prime Minister’s announcement to tackle waiting list backlog
6th January 2025 – Responding to the PM’s announcement this morning to address the waiting list backlog, Mark Bowditch, President of the British Orthopaedic Association…
Current Sports Medicine Reports
Current Sports Medicine Reports is unique in its focus entirely on the clinical aspects of sports medicine. This peer-reviewed journal harnesses the tremendous scientific and…
