David Crawford discusses with Daniel Petrylak a new approach to treating advanced prostate cancer using a PROTAC agent called ARV-766. Dr. Petrylak explains that PROTACs accelerate the body’s natural protein disposal process, targeting the androgen receptor. The phase I/II study of ARV-766 shows promising results in patients with ligand-binding domain mutations, which occur in about 25% of…
Chiara Ciccarese discusses the TACITO-II trial results, evaluating fecal microbiota transplantation (FMT) in patients receiving pembrolizumab plus axitinib for metastatic renal cell carcinoma. The phase…
Ruchika Talwar interviews Benjamin Pockros about his published work in Urology Practice, which explores online tools to reduce financial toxicity for urology patients. Dr. Pockros…
At the World Congress of Endourology and Uro-Technology, Seyedamirvala Saadat presents a study examining factors predicting spontaneous ureteral stone passage. The research, involving 199 patients…
Nicholas James and Gerhardt Attard discuss findings from the STAMPEDE trial, focusing on molecular profiling of prostate cancer tumors. They explore the use of the…
Ashish Kamat engages with Andrea Necchi about the use of next-generation sequencing (NGS) in urothelial carcinoma. Dr. Necchi highlights consensus recommendations from a recent retreat,…
Oliver Sartor discusses radiopharmaceuticals with Germo Gericke. Dr. Gericke emphasizes the potential of targeted radioligand therapies, particularly for advanced cancers. He explores various isotopes, including…
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Rashid Sayyid and Zach Klaassen discuss the PI-CAI Challenge, an international study comparing artificial intelligence (AI) to radiologists in prostate cancer detection using MRI. The…
Oliver Sartor interviews Chris Behrenbruch about radiopharmaceuticals in cancer treatment. Dr. Behrenbruch discusses his passion for nuclear medicine, emphasizing its multidisciplinary nature and potential for…
