Using Hypothalamic Peptides to Treat Alzheimer’s Disease in Mice
The hypothalamus is known to play an important role in aging, but whether peptides secreted by the hypothalamus might be useful against Alzheimer’s and other aging-related diseases hasn’t been clear. In a paper published online on October 31 in Nature Communications, Dongsheng Cai, M.D., Ph.D., and colleagues addressed this question by looking at methylation of DNA—an epigenetic event that can regulate genes and is associated with aging. After comparing DNA methylation of the hypothalamus versus two
