How Risky Are Central Venous Catheters?
To estimate the complication rate of central venous catheters (CVCs), researchers performed a systematic review and meta-analysis of 130 observational
To estimate the complication rate of central venous catheters (CVCs), researchers performed a systematic review and meta-analysis of 130 observational
While they account for a large portion of drug targets, membrane proteins (MPs) present a unique challenge for drug discovery. Peripheral membrane proteins (PMPs), a…
Nucleoporins (nups) in the central channel of nuclear pore complexes (NPCs) form a selective barrier that suppresses the diffusion of most macromolecules while enabling rapid…
Protein folding is driven by the burial of hydrophobic amino acids in a tightly-packed core that excludes water. The genetics, biophysics and evolution of hydrophobic…
Showcasing the best images sent to us from around Berkshire.
Regulation of ion channel expression on the plasma membrane is a major determinant of neuronal excitability, and identifying the underlying mechanisms of this expression is…
Spatial transcriptomics data provide insights into gene expression patterns within tissue contexts, where identifying spatial domains with similar gene expression is crucial. Traditional clustering methods…
Multiplex lateral flow assay (LFA) is a handful diagnostic technology that can identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other common respiratory viruses…
Over the past decade, the connection between APOBEC3 cytosine deaminases and cancer mutagenesis has become increasingly apparent. This growing awareness has created a need for…
Copy number variants (CNVs), structural alterations in the genome involving duplication or deletion of DNA segments, are implicated in various health conditions. Despite their clinical…
The genomes of obligately host restricted bacteria suffer from accumulating mildly deleterious mutations, resulting in a drastic size reduction. Psyllids (Hemiptera) are phloem sap sucking…