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Mashup Score: 6Gene editing improves some blind patients’ vision - 2 hour(s) ago
Technique snips out mutation, allowing a critical protein to be produced
Source: www.science.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 0Vaccination with antigenically complex hemagglutinin mixtures confers broad protection from influenza disease - 2 hour(s) ago
Vaccination with a mixture of hemagglutinin variants increases antibody responses to multiple epitopes including the conserved hemagglutinin stalk.
Source: www.science.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 12
Surprising find in northeastern Jordan could rewrite history of cooking technology
Source: www.science.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 11Progress on priming HIV-1 immunity - 4 hour(s) ago
Four new studies inform on the multistep path to generate broadly active HIV-1 antibodies
Source: www.science.orgCategories: General Medicine News, Future of MedicineTweet-
@ScienceTM @SciImmunology Four new studies across Science, @ScienceTM, and @SciImmunology on priming #HIV-1 immunity “will guide [germline-targeting] programs for inducing broadly neutralizing antibodies against other human pathogens,” argue the authors of a #SciencePerspective. https://t.co/ORnT69nXun https://t.co/T23TTKiLkf
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Mashup Score: 10mRNA-LNP prime boost evolves precursors toward VRC01-like broadly neutralizing antibodies in preclinical humanized mouse models - 4 hour(s) ago
mRNA-LNP prime and boost immunogens can drive the maturation of multiple VRC01 precursors in the same host.
Source: www.science.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 3Heterologous prime-boost vaccination drives early maturation of HIV broadly neutralizing antibody precursors in humanized mice - 4 hour(s) ago
An HIV vaccine first-boost candidate immunogen promoted maturation of VRC01-class antibodies in a humanized mouse model, supporting clinical testing.
Source: www.science.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 2
Germline-targeting (GT) HIV vaccine strategies are predicated on deriving broadly neutralizing antibodies (bnAbs) through multiple boost immunogens. However, as the recruitment of memory B cells (MBCs) to germinal centers (GCs) is inefficient and may be …
Source: www.science.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 4Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates - 4 hour(s) ago
Germline-targeting immunogens hold promise for initiating the induction of broadly neutralizing antibodies (bnAbs) to HIV and other pathogens. However, antibody-antigen recognition is typically dominated by heavy chain complementarity determining region …
Source: www.science.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 12Researchers reflect on the death of billionaire science donor Jim Simons and his charitable impact - 4 hour(s) ago
A brilliant mathematician who made billions on Wall Street, Simons gave heavily to basic science and higher education
Source: www.science.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 87An inflamed brain can trigger psychosis. The search is on for patients who might be cured - 5 hour(s) ago
The discovery of rogue antibodies behind paranoia, hallucinations, and other symptoms could bring a “paradigm shift” to psychiatry
Source: www.science.orgCategories: General Medicine News, Expert PicksTweet
A gene-editing technique has shown modest success at treating a blindness disease, according to new results from a clinical trial. https://t.co/ZRpcb1zQMn