In 1998, the Institute of Medicine defined 3 problems in health care quality: underuse, misuse, and overuse.1 The Institute of Medicine Committee on Better Care at Lower Costs estimated that in 2009, about 30% (or roughly $750 billion) was wasted on excessive administrative expenses, fraud,…
This Viewpoint summarizes the role of the Patent Trial and Appeal Board (PTAB) in reforming the drug patent process to avoid erroneously granted patents; highlights…
In Reply Chen and colleagues raise 2 important points in response to our analysis of beremagene geperpavec (B-VEC) therapy1: the high costs of therapy may…
This cross-sectional study analyzes characteristics of prehospital encounters for youth opioid overdoses and trends before and during the COVID-19 pandemic.
This study assesses erenumab efficacy and safety in patients with nonopioid chronic migraine and medication overuse headaches.
This JAMA Insights in the Communicating Medicine series explores how differences in word choice can affect both visit interactions and visit outcomes in patient encounters.
This economic evaluation assesses changes to patient out-of-pocket spending for oral cancer medications before and after the Inflation Reduction Act.
This case report describes a woman in her mid 30s with diabetes who had been treated with insulin therapy, no history of diabetic ketoacidosis, and…
This cohort study evaluates associations between neighborhood food access in early life and childhood body mass index and risk of obesity.
This randomized clinical trial investigates if direct-to-patient mailed interventions reduce sedative use and improve sleep outcomes in patients.
This mendelian randomization study investigates the association between genetic risk for cardiovascular disease and immune-mediated diseases.
