Vitamin B Complex Treatment Attenuates Local Inflammation after Peripheral Nerve Injury – International Natural Product Sciences Taskforce (INPST)
Abstract Peripheral nerve injury (PNI) leads to a series of cellular and molecular events necessary for axon regeneration and reinnervation of target tissues, among which inflammation is crucial for the orchestration of all these processes. Macrophage activation underlies the pathogenesis of PNI and is characterized by morphological/phenotype transformation from proinflammatory (M1) to an…
