This systematic review and meta-analysis of randomized clinical trials examines use of programmed cell death 1 (PD-1) vs programmed cell death–ligand 1 (PD-L1) treatment in patients with cancer.
This cohort study uses a propensity score–matched analysis to assess suicidal ideation or attempts following exposure to glucagon-like peptide 1 receptor agonists (GLP1R) in adolescents…
This diagnostic study evaluates the ability of multiple skin biopsies to detect prion seeding activity compared with the cerebrospinal fluid (CSF) as a diagnostic biomarker…
This JAMA Insights discusses the expanding PrEP options for preventing HIV, including the considerations for initiation and follow-up and implementation challenges of these medications.
This multicenter randomized clinical trial investigates the efficacy and safety of acupuncture compared with sham acupuncture in patients with chronic sciatica from herniated disk.
This Viewpoint discusses potential benefits and obstacles regarding US Food and Drug Administration (FDA) oversight of laboratory-developed tests.
This cohort study assesses the risk of development of type 2 diabetes in pediatric patients aged 10 to 19 years after receiving a COVID-19 diagnosis…
This cross-sectional study evaluates the frequency of new devices receiving US Food and Drug Administration approval through its 510(k) pathway based on predicate devices that…
This cross-sectional study describes overall and age-specific all-cause excess mortality by race and ethnicity during the COVID-19 public health emergency and assesses whether measured differences…
E-cigarette use among middle- and high-school students declined from 8% in 2023 to 6% in 2024, dropping from an estimated 2.1 million to 1.6 million…
This cross-sectional study describes overall and age-specific all-cause excess mortality by race and ethnicity during the COVID-19 public health emergency and assesses whether measured differences…
