Of the five senses—sight, sound, smell, taste, and touch—recognised by Aristotle (384–322 BCE), sight is arguably the one that people fear losing the most. Apt then that on the second Thursday of October each year we celebrate World Sight Day, a day to focus global attention on the major international public health crises of blindness and vision impairment. Since 75% of vision impairment is…
GLP-1 receptor agonists were originally developed for the treatment of type 2 diabetes, and later of obesity, but there is growing evidence that their benefits…
We found evidence that GLP-1 receptor agonists significantly reduce clinically important kidney events, kidney failure, and cardiovascular events.
Monogenic forms of early onset severe childhood obesity (ie, presenting before the age of 5 years) can occur in the context of pathogenic variants of…
To our knowledge this is the first trial of setmelanotide in patients younger than 6 years old. These results support the benefit of the drug…
According to various guidelines and consensus papers, postoperative radioiodine therapy can be prescribed to patients with differentiated thyroid cancer to achieve one of three goals:…
The non-inferiority of a follow-up strategy compared with postoperative 131I administration in low risk differentiated thyroid cancer was confirmed at 5 years. There is no…
The St Vincent declaration1 calls for monitoring and comparing outcomes of diabetes care against treatment goals as a tool for quality control. National diabetes registries…
Between 2013 and 2022, glycaemic outcomes have improved, parallel to increased use of diabetes technology. Many children had HbA1c higher than the International Society for…
In this Review, we aim to complement the 2023 update of the guidelines of the International Working Group on the Diabetic Foot. We highlight the…
Identifying biomarkers of functional β-cell loss is an important step in the risk stratification of type 1 diabetes. Genetic risk scores (GRS), generated by profiling…
