To identify the incidence and prevalence of type 1 Brugada pattern at Mayo Clinic during 30 years.

An adult man with low-volume liver metastases from grade 3 rectal neuroendocrine tumor (Ki67 index of 25%) sequentially underwent multiple systemic therapies. Gallium (88Ga)-DOTATATE scan showed avid metastases, including a scalp deposit (Figure A, B). He received lutetium (177Lu)-DOTATATE, 200 mCi times 3 cycles. The scalp metastasis was excised 8 days after cycle 3 of 177Lu therapy. Histopathologic evaluation was consistent with a metastasis of his neuroendocrine tumor (Figure C). The tumor showed proliferative arrest, with no tumor cell showing reactivity for Ki67 (Figure D), whereas the nontumorous controls showed variable reactivity.

A patient in his late 60s with a prior history of widely metastatic prostatic adenocarcinoma was treated with androgen deprivation therapy and docetaxel chemotherapy. On follow-up, serum prostate-specific antigen (PSA) levels were undetectable. However, prostate-specific membrane antigen positron emission tomography imaging was suggestive of pelvic lymph node involvement.

A 34-year-old woman with a past medical history of psoriasis, polycystic ovarian syndrome, and a history of coronavirus disease 2019 infection presented to an outside emergency department with a 1-month history of dyspnea and productive cough. The patient was not on any medications at the time of presentation. She is a part-time baker and had returned from a work-related event via plane within the last 7 days. In the emergency department, she presented afebrile (37 °C), normotensive (127/62 mm Hg), tachycardic (sinus, ventricular rate 140-150 beats per minute), tachypneic (respiratory rate of 30 breaths/min), and required 3 L of supplemental oxygen via nasal cannula for oxygen saturation of 99%.

To identify the incidence and prevalence of type 1 Brugada pattern at Mayo Clinic during 30 years.

Lithium is considered the criterion standard medication for the maintenance treatment of bipolar disorder (BD).1 It also serves as an effective augmentation option for treatment-resistant depression and as an antisuicidal agent.2 Despite its superior efficacy in preventing both manic and depressive episodes compared with other mood stabilizers or antipsychotics,1,3 lithium continues to be underutilized in the United States due to concerns regarding the development of chronic kidney disease (CKD).

To assess the association between caregiving and menopause symptom burden in midlife women.

To assess whether the mode and formatting of invitations affect enrollment in a large, decentralized study.