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Mashup Score: 23Intracerebral Hemorrhage: Keep It Simple | Stroke - 1 day(s) ago
The quotation, attributed to Confucius many centuries ago, in our opinion, applies to the evolving story of defining a primary surgical treatment for spontaneous intracerebral hemorrhage. The precise quote is: “Keep it simple and focus on what matters. Don’t let yourself be overwhelmed.”1 The evidence from multiple trials on intracerebral hemorrhage regarding mortality benefit and potential functional benefit directs us toward the simple task of evacuating the clot, similar to our prime focus on opening the artery in ischemic stroke. We need not be overwhelmed by questions about adjustments to patient selection, comparative techniques, and precision timing, for which we do not have conclusive data. We review the consensus results from the recent MISTIE trial (Minimally Invasive Surgery Plus Alteplase in ICH Evacuation) and ENRICH trial (Early Minimally Invasive Removal of Intracerebral Hemorrhage) and articulate remaining questions where further evidence is needed to challenge equipois
Source: www.ahajournals.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 7The Certification Ranking of Stroke Treatment Centers Is... : Journal of Neuroscience Nursing - 2 day(s) ago
l provide varying levels of care with CSCs being the most able to treat all types and complexities of stroke. This undergraduate nursing-led study explored the public’s preference for treatment at different certified stroke treatment centers. METHODS: This study was a prospective nonrandomized observational survey of English-speaking adults at a plasma donation center in the Southwest United States. Subjects completed a 2-minute survey asking whether they would drive to the hospital or call 911 during a suspected stroke, and at which type of hospital they would prefer to be treated. RESULTS: Of 249 respondents, 204 (81.9%) indicated that they would call 911 for hospital transport, and 45 (18.1%) would drive their family member to a hospital. Most respondents (95/248, 38.3%) would prefer treatment at a PSC, 90 (36.3%) preferred an ASRH, 52 (21.0%) preferred a CSC, and 11 (4.4%) preferred a TCSC. There was no association between transportation preference and hospital preference dichotomi
Source: journals.lww.comCategories: General Medicine News, NephrologyTweet-
The Certification Ranking of Stroke Treatment Centers Is Unclear to the General Public https://t.co/nn7iUJpJzQ
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Mashup Score: 4Brazil’s Lula is still under intensive care but making progress after surgery, doctors say - 2 day(s) ago
Doctors say Brazilian President Luiz Inácio Lula da Silva remains in intensive care in a Sao Paulo hospital but is getting better.
Source: apnews.comCategories: General Medicine News, NephrologyTweet-
Brazil’s President Lula to undergo a new procedure after initial surgery for brain bleed https://t.co/8UNZg3Dula https://t.co/wuCgydQxju
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Mashup Score: 14Vascular Neurology Considerations for Antiamyloid Immunotherapy: A Science Advisory From the American Heart Association | Stroke - 2 day(s) ago
Antibodies directed at the amyloid-β peptide offer the prospect of disease-modifying therapy for early-stage Alzheimer disease but also carry the risk of brain edema or bleeding events, collectively designated amyloid-related imaging abnormalities. Introduction of the antiamyloid immunotherapies into practice is therefore likely to present a new set of questions for clinicians treating patients with cerebrovascular disease: Which manifestations of cerebrovascular disease should preclude, or permit, antibody treatment? Is it safe to prescribe amyloid immunotherapies to individuals who require antithrombotic treatment, or to administer thrombolysis to antibody-treated individuals with acute stroke? How should severe amyloid-related imaging abnormalities be managed? This science advisory summarizes the data and key considerations to guide these challenging decisions as the medical community collects further data and experience with these groundbreaking agents.
Source: www.ahajournals.orgCategories: General Medicine News, NephrologyTweet-
Vascular Neurology Considerations for Antiamyloid Immunotherapy: A Science Advisory From the American Heart Association | Stroke https://t.co/o1VSC88kXa
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Mashup Score: 27
Rationale: The benefit of tenecteplase in the treatment of large vessel occlusion (LVO) patients presenting within 24 hours of symptom onset remains unclear. Ai…
Source: journals.sagepub.comCategories: General Medicine News, NephrologyTweet-
Extending the Time Window for Tenecteplase by Effective Reperfusion of Penumbral Tissue in Patients with Large Vessel Occlusion (ETERNAL-LVO) https://t.co/Q7ehkDgszE
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Mashup Score: 12
Background The optimal treatment for carotid free-floating thrombus (CFFT) remains uncertain due to limited evidence, with no randomized clinical trials and sca…
Source: journals.sagepub.comCategories: General Medicine News, NephrologyTweet-
Efficacy and safety of anticoagulant and antiplatelet therapies in the medical management of carotid free-floating thrombus: A systematic review https://t.co/w8bEYbRsLS
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Mashup Score: 3Circulating miRNAs Associated With 3-Month Outcome in Patients With Acute Ischemic Stroke | Neurology - 3 day(s) ago
Background and ObjectivesPost–ischemic stroke (IS) outcomes vary widely among individuals, independently of clinical factors. This variability could be related to epigenetic mechanisms that regulate biological processes involved in recovery after …
Source: www.neurology.orgCategories: General Medicine News, NephrologyTweet-
Circulating miRNAs Associated With 3-Month Outcome in Patients With Acute Ischemic Stroke | Neurology https://t.co/2DYRjvSnBw
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Mashup Score: 22
Transradial arterial access has transformed the field of coronary interventions, where it has several advantages over femoral access, such as reduced bleeding and access site complications, improved patient comfort, shorter time to ambulation after the procedure, reduced length of hospital stay, and potentially reduced mortality rates. Because of these benefits, as well as the concurrent expanding indications for various endovascular therapies, there is growing interest in adopting radial access for peripheral vascular interventions. However, radial access can present challenges, and specialized equipment for peripheral interventions through this route are under development. Nevertheless, a growing number of studies, largely comprising single-center and registry data, have broadly suggested that transradial arterial access is likely to be safe and associated with reduced bleeding and local access site complications for most peripheral interventions compared with transfemoral access. La
Source: www.ahajournals.orgCategories: General Medicine News, NephrologyTweet-
Radial Access Approach to Peripheral Vascular Interventions: A Scientific Statement From the American Heart Association | Circulation: Cardiovascular Interventions https://t.co/PC51eb4rHU https://t.co/GsL5oLKqxE
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Mashup Score: 31Lower Ticagrelor Dosing in the Dual Antiplatelet Regimen for Neurointerventional Procedures - 3 day(s) ago
Background Ticagrelor, a P2Y12 inhibitor, offers a rapid onset and consistent platelet inhibition, making it a viable alternative for dual antiplatelet therapy (DAPT). The optimal ticagrelor dose for neurointerventional procedures, however, remains unclear. We report our experience with ticagrelor 60 mg twice daily plus aspirin 81 mg daily compared with the standard aspirin and clopidogrel regimen for intracranial stenting. Methods We conducted a retrospective analysis of a prospectively maintained database, identifying consecutive patients who underwent intracranial stenting for aneurysm treatment or intracranial atherosclerosis. Patients received either ticagrelor 60 mg with aspirin or aspirin with clopidogrel 75 mg daily. Primary outcomes included peri-procedural ischemic and/or hemorrhagic events within 30 days. Secondary outcomes were the median P2Y12 reaction unit and in-stent stenosis rates at 6-month follow-up. Results Among 119 patients, 59 received ticagrelor and 60 (50.4%) r
Source: jnis.bmj.comCategories: General Medicine News, NephrologyTweet-
Lower Ticagrelor Dosing in the Dual Antiplatelet Regimen for Neurointerventional Procedures https://t.co/EHDs4OfqSE
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Mashup Score: 94Recanalization Does Not Always Equate to Reperfusion: No-Reflow Phenomenon After Successful Thrombectomy | Stroke - 3 day(s) ago
BACKGROUND: Thrombectomy for acute large vessel occlusion is a well-established treatment for stroke prevention. However, futile recanalization cases, where no-reflow occurs despite successful recanalization, have been reported. This study aimed to assess cerebral hemodynamics immediately after thrombectomy and their relationship with clinical outcomes. METHODS: We prospectively enrolled patients who underwent successful thrombectomy (modified Thrombolysis in Cerebral Infarction [TICI] ≥2b) for internal carotid artery or middle cerebral artery occlusions at Nagasaki University Hospital between January 2021 and December 2023. Preoperative magnetic resonance imaging was performed, followed by flat-panel computed tomography perfusion 30 minutes after recanalization. Areas with cerebral blood flow 6 seconds, and cerebral blood volume <34%, 38%, and 42% were analyzed, and hypoperfusion intensity ratio and cerebral blood volume index were calculated using Rapid ANGIO. We assessed
Source: www.ahajournals.orgCategories: General Medicine News, NephrologyTweet-
Recanalization Does Not Always Equate to Reperfusion: No-Reflow Phenomenon After Successful Thrombectomy | Stroke https://t.co/odcylVjoFw https://t.co/M91K9GdmLY
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Intracerebral Hemorrhage: Keep It Simple | Stroke https://t.co/t8JpWNFXe9