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Mashup Score: 10
In families with multiple cases of Crohn’s disease, unaffected members are 3 times more likely to develop the disease, possibly due to environmental factors rather than genetics.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 8Atlas of Metastatic Gastric Cancer Links Ferroptosis to Disease Progression and Immunotherapy Response - 2 day(s) ago
A comprehensive single-cell tumor and immune atlas of metastatic gastric adenocarcinomas is presented, uncovering molecular and cellular dynamics during metastasis and proposing a novel therapeutic strategy with potential clinical implications.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 15Top 20 high-impact clinical research articles of 2024 - 6 day(s) ago
Our editors-in-chief share their selection of must-read clinical research articles from the past year.
Source: gastro.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 26
Potential celiac disease (PCD) is characterized by the presence of anti-tissue transglutaminase antibodies and normal intestinal architecture.1
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 3Pragmatic Resect and Discard Implementation Using Computer-Assisted Optical Polyp Diagnosis - 8 day(s) ago
Histopathology assessment is the current standard of care for evaluating diminutive colorectal polyps. The
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 10Combining Colonoscopy With Fecal Immunochemical Test Can Improve Current Familial Colorectal Cancer Colonoscopy Surveillance: A Modelling Study - 10 day(s) ago
Fecal immunochemical test could play an important role in surveillance for individuals with a family history of colorectal cancer. Ten-yearly colonoscopy and 2-yearly FIT between colonoscopies from ages 40 to 80 years was the optimal strategy.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 6Stool-Based Testing for Post-Polypectomy Colorectal Cancer Surveillance Safely Reduces Colonoscopies: The MOCCAS Study - 13 day(s) ago
Stool-based surveillance strategies were identified that may safely reduce the number of post-polypectomy surveillance colonoscopies. Multitarget stool DNA–based surveillance was more costly than colonoscopy surveillance, and fecal immunochemical test–based surveillance saved costs compared with colonoscopy surveillance.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 4
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with limited treatment options and a 5-year survival rate of just 12.8%.1 Early diagnosis is rare, leading to advanced disease and chemoresistance, which complicates treatment. Current chemotherapeutic regimens, including gemcitabine (GEM), nab-paclitaxel, 5-fluorouracil, oxaliplatin, irinotecan, and FOLFIRINOX, show modest efficacy.2 Novel therapies are urgently needed to improve outcomes and quality of life for PDAC patients.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 1Current Issue Table of Contents: Gastroenterology - 15 day(s) ago
Login with your AGA username and password. Volume 167 Issue 4 p633-820,
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 19Myosin Vb Traffics P-Glycoprotein to the Apical Membrane of Intestinal Epithelial Cells - 17 day(s) ago
The authors use animal models, human biopsy samples, and human cells to demonstrate that MYO5B traffics the drug transporter P-glycoprotein to the apical membrane of intestinal epithelial cells.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
Study finds healthy first-degree relatives from multiplex families vs simplex families have higher subclinical intestinal inflammation, a distinct fecal microbial signature, and harbor a higher risk of developing #CrohnsDisease ➡️ https://t.co/il3z9ohBFz https://t.co/AAMiY1u6Ij