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Cushing’s disease requires accurate diagnosis, careful treatment selection, and long-term management to optimise patient outcomes. The Pituitary Society convened a consensus workshop comprising more...

Integrating DoMore-v1-CRC and pathological staging markers provided a clinical decision support system that risk stratifies more accurately than its constituent elements, and identifies substantially...

The addition of thoracic CT scans during follow-up, which included clinic visits and chest x-rays after surgery, did not result in longer survival among...

In this study, the 5-year locoregional recurrence rate was less than 4%, which supports our hypothesis that it is oncologically safe to de-escalate locoregional...

The addition of galunisertib to neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer improved the complete response rate to 32%, was well tolerated,...

The primary endpoint of 6-month progression-free survival was met in the niraparib plus ipilimumab maintenance group, whereas niraparib plus nivolumab yielded inferior progression-free survival....

Zandelisib 60 mg once daily on an intermittent dosing schedule was safe, with low frequency of grade 3 or worse adverse events, warranting the...

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    ICYMI: #Zandelisib with continuous/intermittent #dosing as monotherapy or in combination with #rituximab in patients with R/R #Bcell malignancy: a multicentre, first-in-patient, phase 1b trial #leusm #lymsm https://t.co/x6z9Nyj0ER - view on twitter

Adding atezolizumab to vemurafenib plus cobimetinib provided promising intracranial activity in patients with BRAFV600-mutated melanoma with CNS...

More radical excisional techniques reduce the risk of treatment failure but increase the risk of subsequent preterm birth. Although there is uncertainty, ablative treatments...

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    Also in the August issue: Comparative effectiveness and risk of #preterm #birth of local #treatments for #cervicalintraepithelialneoplasia and stage IA1 #cervicalcancer: a systematic review and network meta-analysis https://t.co/APwtqyG8me - view on twitter