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The spleen is thought to be the major source of the proinflammatory cytokine TNF during systemic inflammation. However, Fonseca et al. found that the...

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Science

How SARS-CoV-2 first adapted in humans - 1 day

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Viruses need entry proteins to penetrate the cells where they will replicate. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) version is called the...

“We are all stronger if we authentically share and connect with one another,” this grad student...

Extinct species had complex behaviors, just like modern species, but fossils generally reveal little of these details. New approaches that allow for the study...

Inflammasome assembly and activation leading to mature IL-1β release is dysregulated in a wide range of inflammatory diseases. Optimal activation of the NLRP3 inflammasome...

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Science

Water is scarce in dryland ecosystems. Some larger animals in these regions dig wells that may provide water to other species. This behavior may...

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Science Advances

Morphing pasta and beyond - 34 mins

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Morphing structures are often engineered with stresses introduced into a flat sheet by leveraging structural anisotropy or compositional heterogeneity. Here, we identify a simple...

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Science

Expanding cell-to-cell interactions - 3 hours

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High-dimensional single-cell technologies have revolutionized the study of cell biology by unraveling the cellular heterogeneity and molecular complexity that underlies human health and disease....