Mashup Score:187
NatureGenomic profiling informs diagnoses and treatment in vascular anomalies – Nature Medicine - 2 days
Mashup Score:187
Twitter Feed: Pradeep Natarajan
Mashup Score:15
STATMore young people should be getting their cholesterol tested and taking statins - 6 days
Mashup Score:15
National guidelines around screening and treating cholesterol in young adults need to be...
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Current guidelines insufficiently address management of hypercholesterolemia (unless severe) among young adults. Compounded by both under-treatment and under-checking https://t.co/5uav1287Kl @statnews by @suhas_gondi - view on twitter
Mashup Score:13
New York TimesA New Genetic Test Takes Aim at Young Hearts - 5 days
Mashup Score:13
Polygenic risk scores could help patients understand whether they really need early treatment for heart...
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New piece on polygenic risk scores from @ginakolata. Not sure there is much actually new here but it’s a nice summary… https://t.co/hpcU3XzVTt - view on twitter
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Polygenic risk scores could help patients understand whether they really need early preventive treatment for heart disease https://t.co/mTx6yCoSYb by @ginakolata @nytimes - view on twitter
Mashup Score:6
Broad InstituteMulti-ancestry study reveals genetic risk factors for two common pregnancy complications - 3 days
Mashup Score:6
The findings could help doctors identify pregnancies at risk of preeclampsia and gestational hypertension and treat them...
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Multi-ancestry study reveals genetic risk factors for two common pregnancy complications https://t.co/M2z2WJk9HR @broadinstitute [coverage of https://t.co/M2z2WJk9HR @NatureMedicine] https://t.co/M2z2WJk9HR - view on twitter
Mashup Score:4
JAMA NetworkDOACs vs LMWH and Recurrent VTE in Patients With Cancer - 2 days
Mashup Score:4
This randomized trial assesses the comparative effectiveness of direct oral anticoagulants vs low-molecular-weight heparin on rate of 6-month recurrence of venous thromboembolism (VTE) among...
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In an unblinded RCT of 671 pts with cancer and VTE event, DOACs were non-inferior to LMWH w respect to recurrent VTE rate at 6mo (6.1% vs 8.8%) https://t.co/qUuy3ChJV7 @JAMA_current https://t.co/qUuy3ChJV7 - view on twitter
Mashup Score:2
www.nice.org.ukThis guideline covers the assessment and care of adults who are at risk of or who have cardiovascular disease (CVD), such as heart disease...
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Updated UK @NICEComms CVD prevention guidelines do not preclude use of statins for individuals with QRISK3 10-year risk < 10% & indicate shared decision-making https://t.co/myJRJDsD3X https://t.co/myJRJDsD3X - view on twitter
Mashup Score:2
JAMA NetworkManagement of Severe and Moderate Hypercholesterolemia in Young Women and Men - 6 days
Mashup Score:2
This study uses clinical registry data to assess achievement of low-density lipoprotein cholesterol reduction and lipid-lowering therapy prescribing patterns among adults aged 20 to...
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Our prior exploration of the management of young adults with moderate or severe hypercholesterolemia in @MassGenBrigham led by @SNewtonMD @mchonig https://t.co/ksZ2CTREGs @JAMACardio - view on twitter
Mashup Score:2
bioRxivMendelian randomization uses genetic variants as instrumental variables to make causal inferences on the effect of an exposure on an outcome. Due to the...
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New Mendelian randomization method using summary stats may retain power even in high pleiotropy scenarios https://t.co/U5zcHjGWU0 @biorxivpreprint by @andy_grant1 @stevesphd - view on twitter
Mashup Score:1
ScienceDirectGlobal Biobank Meta-analysis Initiative: Powering genetic discovery across human disease - 4 days
Mashup Score:1
Biobanks facilitate genome-wide association studies (GWASs), which have mapped genomic loci across a range of human diseases and traits. However,...
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@ShoaClarke @MitchellLunn @DrMarthaGulati @SmidtHeart @CedarsSinai @MKIttlesonMD @CMAlbertEP @SumeetSChugh @JanetWeiMD @nataliebello9 @CedarsSinaiMed @AllofUsResearch From GBMI pub in @CellGenomics https://t.co/x1dAzwRfww - figure meant to be generally emblematic of genomic data now available within healthcare settings. Lots beyond this figure! - view on twitter
Mashup Score:1
The New YorkerA Cartoon from The New Yorker - 2 days
Mashup Score:1
See more Cartoons on The New...
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OOO enforcement https://t.co/Dy0tPQdfck @newyorkerhumor https://t.co/Dy0tPQdfck - view on twitter
Genomic and cell-free DNA sequencing clarify the clinical diagnosis and inform treatment initiation in a cohort of 356 patients with vascular...
Among a cohort of pts with complex vascular anomalies, tiered deep/ultra-deep sequencing yielded a molecular diagnosis of in most, with a large fraction found to have somatic mosaicism https://t.co/zxFc5mOuTt @NatureMedicine https://t.co/zxFc5mOuTt - view on twitter