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Repair processes in kidney are impaired in severe disease. Here, the authors show that in kidney failure, genetic or pharmacologic inhibition of IL11 releases...

Cinnamon is the inner bark of trees named Cinnamomum. Studies have shown that cinnamon and its bioactive compounds can influence brain function and affect...

Barrier-to-autointegration factor 1 (BAF) is a DNA binding protein involved in numerous pathways including transcriptional regulation, DNA damage response and nuclear assembly. Here, Broussard...

Peptide modification is used to optimize the transport of saporin specifically to cancer cells in vitro and in vivo, where it exerts anti-cancer...

This cohort study assesses whether CYP1A2 genotype modifies the association between caffeine intake and kidney dysfunction among untreated individuals in Italy aged 18 to...

Closed-loop neural interfaces with on-chip machine learning can detect and suppress disease symptoms in neurological disorders or restore lost functions in paralyzed patients. While...

Predicting drug–target interaction with computational models has attracted a lot of attention, but it is a difficult problem to generalize across domains to out-of-distribution...

Depuydt and Schaftenaar et al. profile the T cell clonality in patients with atherosclerosis by performing single-cell T cell receptor sequencing on carotid artery...

Mitchell et al. identify reduced osteoprogenitors and increased mesenchymal stromal cells in old bone marrow niche, which creates an IL1-mediated inflammatory milieu that skews...

The human brain prepares skilled movements such as playing the piano, competing in athletics, or dancing by “zipping and unzipping” information about the timing...