Mashup Score:5167
Centers for Disease Control and Preve...COVID Data Tracker - 1 week
Mashup Score:5167
Twitter Feed: Eric Topol
Background The emergence of SARS-CoV-2 variants has significantly reduced the efficacy of some approved vaccines. A fourth dose of NVX-CoV2373 (5μg SARS-CoV-2 rS +...
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Encouraging new data for @Novavax boosters (1st and 2nd) for inducing neutralizing antibody response vs BA.5 https://t.co/CmpPueCwuG https://t.co/CmpPueCwuG - view on twitter
Mashup Score:852
bioRxivMolecular and cellular similarities in the brain of SARS-CoV-2 and Alzheimer’s disease individuals - 5 days
Mashup Score:852
Infection with the etiological agent of COVID-19, SARS-CoV-2, appears capable of impacting cognition, which some patients with Post-acute Sequelae of SARS-CoV-2 (PASC). To evaluate...
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Common threads between #SARSCoV2 brain involvement and Alzheimer's disease at post-mortem: pattern of neuroinflammation and gene expression, microglia nodule formation, pathway activation, and vascular injury https://t.co/ln41iwTlvG @Pasing01 @IcahnMountSinai @IcahnCMIN https://t.co/ln41iwTlvG - view on twitter
More coverage:
#sarscov2
Mashup Score:819
medRxivImportance: While a substantial fraction of the US population was infected with SARS-CoV-2 during December 2021-February 2022, the subsequent evolution of population immunity against...
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As of 10 November 2022, it is estimated that 94% of Americans have had Covid at least once, much of those infections in the past year. Ranking of states w/ most vulnerability d/t lack of vaccines/ boosters https://t.co/W5zzyrD0vN @HarvardChanSPH https://t.co/W5zzyrD0vN - view on twitter
Mashup Score:729
New York TimesWhat if You Could Go to the Hospital … at Home? - 1 week
Mashup Score:729
Hospital-at-home care is an increasingly common option, and it is often a safer one for older adults. But the future of the approach depends...
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“Americans have been trained for 100 years to think that the hospital is the best place to be, the safest place. But we have strong evidence that the outcomes are actually better at home.” The hospital-at-home movement is just getting started https://t.co/TnfDzSCeoK @paula_span https://t.co/TnfDzSCeoK - view on twitter
Mashup Score:658
erictopol.substack.comThe BQ.1.1 variant story - 2 days
Mashup Score:658
Overall, a very good look and omen for the next couple of...
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Despite David Ho and colleagues new preprint, I wrote that the concerns over these variants have yet to be clinically manifest. It's the 1st time in the pandemic that lab assays of marked increases in immune evasion have not played out w/ new major surges https://t.co/DqMJ7LSJZC - view on twitter
Mashup Score:624
erictopol.substack.comThe BQ.1.1 variant story - 7 days
Mashup Score:624
Overall, a very good look and omen for the next couple of...
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This is about the short term outlook only, as I reviewed here https://t.co/DqMJ7LAALu ⚠️ still needed - view on twitter
Mashup Score:614
erictopol.substack.comThe BQ.1.1 variant story - 1 week
Mashup Score:614
Overall, a very good look and omen for the next couple of...
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Unlike the prior 2 holiday seasons in the US, a major surge is unlikely, which is not in keeping with new, dominant variants with marked immune evasion. https://t.co/DqMJ7LAALu However, waning of immunity, poor uptake of boosters, and lack of mitigation sets up vulnerability https://t.co/DqMJ7LAALu - view on twitter
Mashup Score:406
Annals of Internal MedicineBackground: It is uncertain if medical masks offer similar protection against COVID-19 compared with N95 respirators. Objective: To determine whether medical masks are noninferior...
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A randomized trial of medical masks vs N95s in health care workers to prevent Covid https://t.co/CSJkFLE15z —It's woefully underpowered but ruled out a doubling of hazard for use of medical masks —In 3 of the 4 countries there was less risk with N95s (p=NS) https://t.co/CSJkFLE15z - view on twitter
Mashup Score:334
Centers for Disease Control and Preve...Paxlovid Associated with Decreased COVID-19 Hospitalizations .. - 1 week
Mashup Score:334
This report describes how eligible adults prescribed Paxlovid were...
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Illuminating new @CDCMMWR repot for real world Paxlovid reduction of hospitalization by ~50% across all subgroups by age, vaccinated status, prior infection, month of infection (proxy for variant) https://t.co/LoMLSPepmd https://t.co/LoMLSPepmd - view on twitter
CDC’s home for COVID-19 data. Visualizations, graphs, and data in one easy-to-use...
New @CDCgov data for reduction of deaths by vaccination/boosters for age 12+ through September 2022 https://t.co/HGyjNwCm0v https://t.co/HGyjNwCm0v - view on twitter