Proteomics analysis of adipose depots after intermittent fasting reveals visceral fat preservation mechanisms
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Cell Reports - Harney et al. show that every-other-day fasting improves metabolic health in mice in the absence of weight loss and examine the proteomic response of several...
Tracing cell-type evolution by cross-species comparison of cell atlases
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Cell Reports - Wang et al. use organism-wide single-cell transcriptomes to comprehensively characterize the conservation and divergence of cell types during animal evolution. They propose cell-type evolutionary hierarchy...
Tracing cell-type evolution by cross-species comparison of cell atlases https://t.co/qzRUPbdCHx
MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity
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Cell Reports - Branigan et al., by using genome-wide CRISPR screens, identify the MMB-FOXM1 complex as being required for CHK1 inhibitor (CHK1i) sensitivity. Their study shows that CHK1i-induced...
MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity https://t.co/Wmh7UQ2X6Q
High-resolution phenotyping of early acute rejection reveals a conserved alloimmune signature
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Cell Reports - Harden et al. show that unsupervised high-dimensional CyTOF analysis identifies an alloimmune signature that specifically distinguishes rejecting from non-rejecting transplants. This signature is revealed by...
Mass cytometry shows the immune cell signature associated with transplant rejection https://t.co/9muuNrUGia
Cell Reports - Schlesiger et al. show that two distinct inhibitory projections from the septal region differentially control temporal coding and burst firing of spatially tuned neurons in...
Two septal-entorhinal GABAergic projections differentially control coding properties of spatially-tuned neurons in the medial entorhinal cortex https://t.co/Q6Dstnk1Ee
Atx regulates skeletal muscle regeneration via LPAR1 and promotes hypertrophy
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Cell Reports - Satellite cells are indispensable for skeletal muscle formation or repair post-injury. Ray et al. identify that autotaxin (Atx) regulates the function of satellite cells through...
Atx regulates skeletal muscle regeneration via LPAR1 and promotes hypertrophy https://t.co/TI9mZAb7WF
virtual.keystonesymposia.org - Joint with: Precision Engineering of the Genome, Epigenome and Transcriptome Improvements in plant breeding are necessary to feed a...
Join Cell Reports editor Rita Gemayel for the @KeystoneSymp virtual #eSymposia, Plant Genome Engineering: From Lab to Field, to explore emerging research in #PlantGenetics technologies and and tools. Register today at https://t.co/ifFcWk3G4r #VKSPlant21 https://t.co/ifFcWk3G4r
Cell Reports - Rosario et al. reveal the role of gut microbiome in Parkinson’s disease (PD) through functional and compositional analysis and genome-scale metabolic modeling. Microbial capability of...
Systematic Analysis of Gut Microbiome Reveals the Role of Bacterial Folate and Homocysteine Metabolism in Parkinson’s Disease https://t.co/TBnJS4HRbe
Cell Reports - Schneid et al. show that the three BRCT domains of ECT2 make distinct contributions to RhoA zone formation and cytokinesis. BRCT0 and BRCT1 bind RACGAP1...
The BRCT domains of ECT2 have distinct functions during cytokinesis https://t.co/gqKo0W5Ygg
Cell Reports - Dong et al. show that SYTL3 is involved in early human cortical development. Using the NetBio2 algorithm, they demonstrate that SYTL3 displays a high activity...
Transcriptional networks identify synaptotagmin-like 3 as a regulator of cortical neuronal migration during early neurodevelopment https://t.co/yhiIXRg2dj
Proteomic analysis of adipose depots after intermittent fasting https://t.co/bChn0QIZ0A