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Proteomics analysis of adipose depots after intermittent fasting reveals visceral fat preservation mechanisms

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Cell Reports - Harney et al. show that every-other-day fasting improves metabolic health in mice in the absence of weight loss and examine the proteomic response of several...

Tracing cell-type evolution by cross-species comparison of cell atlases

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Cell Reports - Wang et al. use organism-wide single-cell transcriptomes to comprehensively characterize the conservation and divergence of cell types during animal evolution. They propose cell-type evolutionary hierarchy...

MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity

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Cell Reports - Branigan et al., by using genome-wide CRISPR screens, identify the MMB-FOXM1 complex as being required for CHK1 inhibitor (CHK1i) sensitivity. Their study shows that CHK1i-induced...

High-resolution phenotyping of early acute rejection reveals a conserved alloimmune signature

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Cell Reports - Harden et al. show that unsupervised high-dimensional CyTOF analysis identifies an alloimmune signature that specifically distinguishes rejecting from non-rejecting transplants. This signature is revealed by...

Cell Reports - Schlesiger et al. show that two distinct inhibitory projections from the septal region differentially control temporal coding and burst firing of spatially tuned neurons in...

  • Two septal-entorhinal GABAergic projections differentially control coding properties of spatially-tuned neurons in the medial entorhinal cortex https://t.co/Q6Dstnk1Ee

Atx regulates skeletal muscle regeneration via LPAR1 and promotes hypertrophy

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Cell Reports - Satellite cells are indispensable for skeletal muscle formation or repair post-injury. Ray et al. identify that autotaxin (Atx) regulates the function of satellite cells through...

Plant Genome Engineering: From Lab to Field | EK25

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virtual.keystonesymposia.org - Joint with: Precision Engineering of the Genome, Epigenome and Transcriptome Improvements in plant breeding are necessary to feed a...

Cell Reports - Rosario et al. reveal the role of gut microbiome in Parkinson’s disease (PD) through functional and compositional analysis and genome-scale metabolic modeling. Microbial capability of...

The BRCT domains of ECT2 have distinct functions during cytokinesis

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Cell Reports - Schneid et al. show that the three BRCT domains of ECT2 make distinct contributions to RhoA zone formation and cytokinesis. BRCT0 and BRCT1 bind RACGAP1...

Cell Reports - Dong et al. show that SYTL3 is involved in early human cortical development. Using the NetBio2 algorithm, they demonstrate that SYTL3 displays a high activity...