Mashup Score:75
Cancer CellTargeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis - 1 week
Mashup Score:75
Twitter Feed: Cancer Cell
Mashup Score:73
Cancer CellMetabolic programming and immune suppression in the tumor microenvironment - 1 week
Mashup Score:73
Arner and Rathmell discuss how metabolic programs within tumors depend not only on the tumor microenvironment (TME) cellular composition but also on cell states,...
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"Metabolic Programming and Immune Suppression in the Tumor Microenvironment", take a look from @JeffRathmell discussing the metabolic crosstalk and requirements of tumor cells and their surroundings https://t.co/SKbgjgJYFQ https://t.co/SKbgjgJYFQ - view on twitter
Mashup Score:52
Cancer CellNeutralizing IL-8 potentiates immune checkpoint blockade efficacy for glioma - 6 days
Mashup Score:52
Massive MDSC infiltration, pro-tumor TAM polarization, and angiogenesis in glioma constitute barriers to counteract ICB-elicited antitumor immunity. Liu et al. show that IL-8, derived from...
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Online Now: Neutralizing IL-8 potentiates immune checkpoint blockade efficacy for glioma https://t.co/OkqOO4jPnx - view on twitter
Mashup Score:22
Cancer CellChallenges and opportunities for modeling aging and cancer - 2 hours
Mashup Score:22
Age is among the main risk factors for cancer, and any cancer study in adults is faced with an aging tissue and organism. Yet,...
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Online Now: Challenges and opportunities for modeling aging and cancer https://t.co/k5JTtHYXN9 https://t.co/k5JTtHYXN9 - view on twitter
Mashup Score:14
Cancer CellEpithelial cells activate fibroblasts to promote esophageal cancer development - 1 week
Mashup Score:14
Chen et al. perform single-cell and spatial transcriptomic analyses of multistage esophageal lesions and reveal gradual loss of ANXA1 expression in epithelial cells during ESCC...
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Online Now: Epithelial cells activate fibroblasts to promote esophageal cancer development https://t.co/Y75uYYoE8W - view on twitter
Mashup Score:12
Cancer CellImmune checkpoint blockade has reached the standard of care for patients with lung cancer. However, its mode of action in patients is still incompletely...
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Online Now: A progressive T cell exhaustion program mapped across tissues in patients with lung cancer on immune checkpoint blockade https://t.co/0vzFhi3SFz https://t.co/0vzFhi3SFz - view on twitter
Modulating the tumor immune microenvironment in a molecularly defined manner remains a major challenge. Zhou et al report a molecular mechanism of ARID1A regulated immuno-stimulatory...
Online Now: Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis https://t.co/cAl3kO4ztv - view on twitter