Mashup Score:21
bioRxivTwitter Feed: bioRxiv
Mashup Score:16
bioRxivRapid and accurate deorphanization of ligand-receptor pairs using AlphaFold - 1 week
Mashup Score:16
Secreted proteins are extracellular ligands that play key roles in paracrine and endocrine signaling, classically by binding cell surface receptors. Experimental assays to identify...
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Rapid and accurate deorphanization of ligand-receptor pairs using AlphaFold https://t.co/n8es5WDpF2 #bioRxiv - view on twitter
Mashup Score:7
bioRxivMechanisms of transcription control by distal enhancers from high-resolution single-gene imaging - 6 days
Mashup Score:7
How distal enhancers physically control promoters over large genomic distances, to enable cell-type specific gene expression, remains obscure. Using single-gene super-resolution imaging and acute...
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Mechanisms of transcription control by distal enhancers from high-resolution single-gene imaging https://t.co/77fkQsSucZ #bioRxiv - view on twitter
Mashup Score:7
bioRxivHow total mRNA influences cell growth - 5 days
Mashup Score:7
While the conventional wisdom is that growth rate is prominently set by ribosome amounts, in many biologically relevant situations the levels of mRNA and...
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How total mRNA influences cell growth https://t.co/tXOAJfZbT8 #bioRxiv - view on twitter
Mashup Score:7
bioRxivSelf-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo - 6 days
Mashup Score:7
Guide RNAs offer programmability for CRISPR-Cas9 genome editing but also add challenges for delivery. Chemical modification, which has been key to the success of...
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Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo https://t.co/mBEUJChgYc #bioRxiv - view on twitter
Mashup Score:7
bioRxivDiverse and Abundant Viruses Exploit Conjugative Plasmids - 7 days
Mashup Score:7
Viruses exert profound evolutionary pressure on bacteria by interacting with receptors on the cell surface to initiate infection. While the majority of bacterial viruses,...
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Diverse and Abundant Viruses Exploit Conjugative Plasmids https://t.co/GT1WUnlhOd #bioRxiv - view on twitter
Mashup Score:7
bioRxivIdentification of mammalian transcription factors that bind to inaccessible chromatin - 1 week
Mashup Score:7
Transcription factors (TFs) are proteins that affect gene expression by binding to regulatory regions of DNA in a sequence specific manner. The binding of...
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Identification of mammalian transcription factors that bind to inaccessible chromatin https://t.co/DguF9IfAaD #bioRxiv - view on twitter
Mashup Score:6
bioRxivIntake of Western diet stimulates bile acid (BA) production and their conversion to secondary BAs by 7α-dehydroxylating (7αDH+) bacteria in the colon. Increased levels...
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Secondary bile acid production by gut bacteria promotes Western diet-associated colorectal cancer https://t.co/dx7X2lYDpy #bioRxiv - view on twitter
Mashup Score:6
bioRxivPrimate TRIM34 is a broadly-acting, TRIM5-dependent lentiviral restriction factor - 22 hours
Mashup Score:6
Human immunodeficiency virus (HIV) and other lentiviruses adapt to new hosts by evolving to evade host-specific innate immune proteins that differ in sequence and...
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Primate TRIM34 is a broadly-acting, TRIM5-dependent lentiviral restriction factor https://t.co/7X5x8Pq3To #bioRxiv - view on twitter
Mashup Score:6
bioRxivFaithful DNA replication requires that cells fine-tune their histone pool in coordination with cell-cycle progression. Replication-dependent histone biosynthesis is initiated at a low level...
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Cyclin E/CDK2 and feedback from soluble histone protein regulate the S phase burst of histone biosynthesis https://t.co/GAFUoSkRTQ #bioRxiv - view on twitter
Traditional genome-editing reagents such as CRISPR-Cas9 achieve targeted DNA modification by introducing double-strand breaks (DSBs), thereby stimulating localized DNA repair by endogenous cellular repair...
Targeted DNA integration in human cells without double-strand breaks using CRISPR RNA-guided transposases https://t.co/lj5aPihHw0 #bioRxiv - view on twitter