Although international consensus exists that dose intensification improves outcomes for patients with radiographically localised Ewing sarcoma, treatment strategies to achieve this intensification, and how to translate this improvement to patients with metastatic disease, has remained controversial and enigmatic.1–4 An intercontinental divide for the upfront treatment of Ewing sarcoma has…
The Cass Review into gender identity services for children and young people will lead to a new holistic model of care within paediatrics in England.…
China is home to the second largest population of children and adolescents in the world. Yet demographic shifts mean that the government must manage the…
Polycystic ovary syndrome (PCOS) is a lifelong chronic condition that affects one in ten females and can be diagnosed in adolescence. As adolescents with PCOS…
Despite tremendous advances in breast cancer research and treatment over the past three decades—leading to a more than 40% reduction in breast cancer mortali…
The Lancet Breast Cancer Commission—a diverse, multidisciplinary international group—are unanimous in our determination to improve the lives of all people who live with or are…
ORBITA-COSMIC found no evidence that the CSR improved transmural myocardial perfusion, but the CSR did improve angina compared with placebo. These findings provide evidence for…
Recognition of misinformation as a public health threat and interest in infodemics, defined as an inundation of information accompanying an epidemic or acute health event,…
The COVID-19 pandemic has highlighted how infodemics (defined as an overabundance of information, including misinformation and disinformation) pose a threat to public health and could…
A 26-year-old woman with a 2-year history of swelling of her eyelids and reduced vision was referred to our clinic by an ophthalmologist because of…
