The VCBS superfamily, a diverse group of β-propellers that includes tachylectin and integrins

β-Propellers are found in great variety across all kingdoms of life. They assume many cellular roles, primarily as scaffolds for macromolecular interactions and catalysis. Despite their diversity, most β-propeller families clearly originated by amplification from the same ancient peptide – the β-propeller blade. In cluster analyses, β-propellers of the WD40 superfamily always formed the largest…

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Source: bioRxiv
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