The Extra-Uterine Environment for Neonatal Development (EXTEND) aims to avoid the complications of prematurity, such as NEC. Our goal was to determine if bowel development occurs normally in EXTEND-supported lambs, with specific emphasis on markers of immaturity associated with NEC.
In the largest study of its kind, we identified key molecular changes that contribute to the spread of stomach cancer to the peritoneum (the lining…
Patients with Crohn’s disease and healthy infants share a dominant immunoglobulin G antibody response to the “hinge region” of Lachnospiraceae flagellins, suggesting that failure of…
A comprehensive single-cell tumor and immune atlas of metastatic gastric adenocarcinomas is presented, uncovering molecular and cellular dynamics during metastasis and proposing a novel therapeutic…
ERCP-associated AEs remain common. Incidence of post-ERCP pancreatitis remained static despite improvements in techniques, prevention, and recognition. These results are important to patients, endoscopists, and…
In a public health model in resource-constrained regions, treatment of hepatitis C virus with generic, free-of-cost, directly acting antiviral agents in patients with decompensated cirrhosis…
The pathophysiology of Crohn’s-like disease of the pouch in patients with a prior history of ulcerative colitis is revealed and new targets to better treat…
The identification of colorectal cancer (CRC) molecular subtypes has prognostic and potentially diagnostic value for patients, yet reliable subtyping remains unavailable in the clinic. The…
Present in all eukaryotic cells, the integrated stress response (ISR) is a highly coordinated signaling network that controls cellular behavior, metabolism, and survival in response…
HTR1A antagonist, such as alverine, decreases portal hypertension in preclinical animals by targeting the portal vein and is expected to become a candidate for the…
Login with your AGA username and password. Volume 165 Issue 2 p307-522,
