The cooperative assembly of shelterin bridge provides a kinetic gateway that controls telomere length homeostasis

AUTS2 mutations often exhibit neurodevelopmental disorders and microcephaly. However, how AUTS2 regulates neuron production and affects brain size remains unclear. Here, we show that AUTS2…

In order to forage for food, many animals regulate not only specific limb movements but the statistics of locomotor behavior over time, for example switching…

Homologous recombination is a meiotic process that generates diversity along the genome and interacts with all evolutionary forces. Despite its importance, studies of recombination landscapes…

The elongation of C. elegans embryos allows examination of mechanical interactions between adjacent tissues. Muscle contractions during late elongation induce the remodelling of epidermal circumferential…

Mechanosensory hair cells located in the inner ear mediate the sensations of hearing and balance. If damaged, mammalian inner ear hair cells are unable to…

The structure and dynamics of the cell nucleus regulate nearly every facet of the cell. Changes in nuclear shape limit cell motility and gene expression.…