Temporal Improvements in COVID-19 Outcomes for Hospitalized Adults: A Post Hoc Observational Study of Remdesivir Group Participants in the Adaptive COVID-19 Treatment Trial | Annals of Internal Medicine

Background: The COVID-19 standard of care (SOC) evolved rapidly during 2020 and 2021, but its cumulative effect over time is unclear. Objective: To evaluate whether recovery and mortality improved as SOC evolved, using data from ACTT (Adaptive COVID-19 Treatment Trial). Design: ACTT is a series of phase 3, randomized, double-blind, placebo-controlled trials that evaluated COVID-19 therapeutics…

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Source: Annals of Internal Medicine

Categories: General Medicine Journals and Societies, Latest Headlines

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Study of standard-of-care #COVID19 measures found improvements in recovery and mortality over time in adults hospitalized with COVID-19: https://t.co/5uFoLKCi3c @NIH https://t.co/eHYmiZ1SZc

Watermelon-Induced Hyperkalemia: A Case Series | Annals of Internal Medicine: Clinical Cases

Hyperkalemia is a potentially life-threatening electrolyte disorder. In patients with stable chronic kidney disease, on stable doses of renin–angiotensin–aldosterone system inhibitors and with adequate distal…

Annals of Int Med April 19, 2024

Effect of Isocaloric, Time-Restricted Eating on Body Weight in Adults With Obesity: A Randomized Controlled Trial: Annals of Internal Medicine: Vol 0, No 0

Background: Time-restricted eating (TRE) lowers body weight in many studies. Whether TRE induces weight loss independent of reductions in calorie intake, as seen in rodent…

Annals of Int Med April 19, 2024

Assessing Clinician Utilization of Next-Generation Antibiotics Against Resistant Gram-Negative Infections in U.S. Hospitals: A Retrospective Cohort Study: Annals of Internal Medicine: Vol 0, No 0

Background: The U.S. antibiotic market failure has threatened future innovation and supply. Understanding when and why clinicians underutilize recently approved gram-negative antibiotics might help prioritize…

Annals of Int Med April 19, 2024

A Rare Case of Disseminated Coccidioidomycosis Presenting as an Intracardiac Mass | Annals of Internal Medicine: Clinical Cases

A 26-year-old immunocompetent male with a history of disseminated coccidioidomycosis presented with shortness of breath for 2 weeks. Computed tomography showed a right paratracheal mass…

Annals of Int Med April 19, 2024

Newer Pharmacologic Treatments in Adults With Type 2 Diabetes: A Clinical Guideline From the American College of Physicians | Annals of Internal Medicine

Description: The American College of Physicians (ACP) developed this clinical guideline to update recommendations on newer pharmacologic treatments of type 2 diabetes. This clinical guideline…

Annals of Int Med April 19, 2024

Effect of Isocaloric, Time-Restricted Eating on Body Weight in Adults With Obesity: A Randomized Controlled Trial: Annals of Internal Medicine: Vol 0, No 0

Background: Time-restricted eating (TRE) lowers body weight in many studies. Whether TRE induces weight loss independent of reductions in calorie intake, as seen in rodent…

Annals of Int Med April 19, 2024

Assessing Clinician Utilization of Next-Generation Antibiotics Against Resistant Gram-Negative Infections in U.S. Hospitals: A Retrospective Cohort Study: Annals of Internal Medicine: Vol 0, No 0

Annals of Int Med April 19, 2024

Effect of Yoga on Frailty in Older Adults: A Systematic Review: Annals of Internal Medicine: Vol 176, No 4

Background: Yoga, a multicomponent mind–body practice, improves several domains of physical and psychological health and may affect frailty in older adults. Purpose: To evaluate the…

Annals of Int Med April 18, 2024

Comparative Efficacy and Safety of Wakefulness-Promoting Agents for Excessive Daytime Sleepiness in Patients With Obstructive Sleep Apnea: A Systematic Review and Network Meta-analysis: Annals of Internal Medicine: Vol 176, No 5

Background: Excessive daytime sleepiness (EDS) is common among patients with obstructive sleep apnea (OSA). The comparative effectiveness of pharmacologic agents is unknown. Purpose: To compare…

Annals of Int Med April 18, 2024

Effect of Yoga on Frailty in Older Adults: A Systematic Review: Annals of Internal Medicine: Vol 176, No 4

Background: Yoga, a multicomponent mind–body practice, improves several domains of physical and psychological health and may affect frailty in older adults. Purpose: To evaluate the…

Annals of Int Med April 18, 2024

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