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    September 25, 2023 —  After world’s first successful transplant in 2022, also performed at the University of Maryland Medical Center (UMMC), this groundbreaking transplant team performed second pig heart transplant on patient deemed ineligible for traditional heart transplant.  A 58-year-old patient with terminal heart disease became the second patient in the world to receive a historic transplant of a genetically-modified pig heart on September 20. He is recovering and communicating with his loved ones. This is only the second time in the world that a genetically modified pig heart has been transplanted into a living patient.  Both historic surgeries were performed by University of Maryland School of Medicine (UMSOM) faculty at the University of Maryland Medical Center (UMMC).  The first historic surgery, performed in January, 2022, was conducted on David Bennett by University of Maryland Medicine surgeons (comprising UMSOM and UMMC), who are recognized as the leaders in cardiac xenot

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    • @DAICeditor @UMmedschool Landmark #cardiac #xenotransplantation procedure conducted at University of Maryland Medical Center: https://t.co/cXPNjKy2Cp #pigheart @artificialheart #transplant

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    Wednesday, 19 April, 2023 FEATURED ABSTRACTS After an exciting conference welcome from program chairs Andreas Zuckermann, MD and Howard Eisen, MD, this featured abstract was introduced wherein Sebastien Hascoet, MD, PhD and colleagues from Marie Lannelongue Hospital in Paris, France presented a retrospective cohort study comparing 61 consecutive pediatric patients with severe pulmonary artery…

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    • Saturday in HEART #ISHLT2023: @JasonGoldbergMD, @LuiseHolzhauser, and #PeiJunZhao covered #PedsTx outcomes, multi-organ transplantation, and novel research in mitochondria and #xenotransplantation. https://t.co/j1iOa8ebKt https://t.co/0ZwfLCS7FO

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    This Review summarizes the current state of knowledge regarding immunological barriers to xenotransplantation and discusses the major approaches that are being used to overcome these barriers, including immunosuppression, genetic engineering of pigs and tolerance induction.

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    • Tolerance and immune function with transplantation of swine (or hybrid) thymus and mixed xenogeneic chimerism. #xenotransplantation https://t.co/sX73Aywzft https://t.co/MISxUdlcFl

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    Abstract. For many patients with terminal/advanced cardiac failure, heart transplantation is the most effective, durable treatment option, and offers the best p

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    • New state-of-the-art #CardiovascularResearch Review on #heart #transplants using genetically multi-modified pig hearts From safety to efficacy, concept to clinic, is #xenotransplantation a bridge to the future? https://t.co/e12oCNXxnv @CVR_TomaszGuzik @DrMikeDrozd @glenpyle https://t.co/8eQzT9G3Ly