• Mashup Score: 0

    Compared with warfarin, direct oral anticoagulants were associated with reduced risk for dementia in patients with atrial fibrillation, particularly those from Asian populations, according to a systematic review and meta-analysis. “Asian patients are more likely to be sensitive to vitamin K antagonism, which puts them at high risk for bleeding events, contributing to dementia development or

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    • Compared with #warfarin, DOACs were associated with reduced risk for #dementia in patients with #AFib, particularly those from Asian populations, according to a systematic review and meta-analysis @ACCinTouch @HealioPsych #cardiotwitter https://t.co/L2pf96Vvef

  • Mashup Score: 2

    Background and Objectives: Ischemic stroke despite direct oral anticoagulant (DOAC) is increasingly common and portends high risk of subsequent ischemic stroke. Efficacy and safety of antithrombotic regimens following the condition are unclear. We aimed to compare the outcomes of patients with ischemic stroke despite DOAC with and without an alternative antithrombotic regimen, and determine the…

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    • Via @GreenJournal: Continuing use of direct oral anticoagulants in patients with non-valvular #AtrialFibrillation after an ischemic #stroke more effectively prevents another stroke than switching to a related drug or #warfarin: https://t.co/bQChQ6rbWu #neurotwitter @AANMember https://t.co/Nigvv1Q5uL

  • Mashup Score: 0

    A vitamin K antagonist such as warfarin, rather than a direct oral anticoagulant, appears to be a better treatment for patients with thrombotic antiphospholipid syndrome, a new meta-analysis suggests.

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    • #Warfarin best for thrombotic #AntiphospholipidSyndrome? 👉https://t.co/uNkSRVr1Su @MDEdgeHemOnc @Hughesedits4u #DOAC https://t.co/3fAZaTyy3v

  • Mashup Score: 2

    Abstract Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is associated with substantial increases in the risk for stroke and systemic thromboembolism. With the successf…

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    • Clinical Recs on 🌏 Population: #Stroke Prevention in #AFib #NOACs have replaced #warfarin for CVA prevention in most clinical settings; #JACCAsia provides updated scientific statements on CVA prevention for AF in Asian patients. https://t.co/ARihLgSakj #cvPrev #ACCIntl https://t.co/HTQnYT3LnZ

  • Mashup Score: 5

    The PROACT Xa trial of apixaban has been stopped due to an excess risk of blood clots compared with warfarin.

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    • Another #DOAC Fails in the Setting of Mechanical Heart Valves The #PROACT Xa trial of apixaban has been stopped due to an excess risk of blood clots compared with #warfarin @TCTMD @ShelleyWood2 @ToddNeale @ErinMichos @mmamas1973 @iamritu @dr_benoy_n_shah https://t.co/8pP7xrKiEX